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2,400+ Python Developer Jobs in the USA

Updated 7 Oct 2026 · 733 new this week · 1 quick-apply roles listed first

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Showing 601–620 of 2,487 jobs

Akamai Technologies logo

Senior Software Engineer

Akamai Technologies5,001–10,000 employees

United StatesRemote5+ yrs$121k–219k

5+ years relevant experience and a Bachelor's degree in Computer Science or related field; experience with distributed systems, Linux networking, TCP/IP, SSH, SSL, HTTP; proficiency in…

  • C
  • C++
  • Go
  • Java
1 week agoApply ↗
Akamai Technologies logo

Senior Software Engineer - Linux Kernel Development

Akamai Technologies5,001–10,000 employees

United StatesRemote5+ yrs$121k–219k

5+ years relevant experience and Bachelor's degree or equivalent; 3+ years C development with Linux kernel focus and scripting (Perl/Python/Shell); solid Linux kernel internals and debugging…

  • Linux
  • C
  • Perl
  • Python
1 week agoApply ↗
Akamai Technologies logo

Senior II Software Engineer - Linux Kernel Development

Akamai Technologies5,001–10,000 employees

United StatesRemote8+ yrs$146k–264k

8+ years relevant experience with Bachelor's degree or equivalent; 3+ years C development focused on Linux kernel; Linux kernel internals and debugging; familiarity with memory management…

  • C
  • Perl
  • Python
  • Shell
1 week agoApply ↗
Hippocratic AI logo

Senior Fullstack Engineer, Reinforced Learning

Hippocratic AI51–200 employees

Menlo ParkOn-site5+ yrsSalary not disclosed

Bachelor's degree in Computer Science or related field; 5+ years full stack development with TypeScript/React and Python, Ruby, or Node; RESTful APIs; SQL/Postgres; cloud platforms; agile methodology.

  • TypeScript
  • React
  • Material UI
  • Python
1 week agoApply ↗
General logo

Applied Robotics Engineer

General201–500 employees

WashingtonOn-site5+ yrs$180k–300k

5+ years deploying AI or robotics systems from prototype to production; strong Python and PyTorch; experience with inference optimization (quantization, distillation, TensorRT, ONNX); depth in policy…

  • Python
  • PyTorch
  • C++
  • Tensorrt
1 week agoApply ↗
SmithRx logo

Staff Systems Engineer

SmithRx501–1,000 employees

PlanoRemote8+ yrs$136k–160k

8+ years in systems engineering or IT infrastructure; deep expertise in Microsoft EntraID, Intune, Autopilot, Windows OS; advanced PowerShell/Python scripting; experience with CloudPC/AVD, HIPAA/SOC…

  • Microsoft Entraid
  • Microsoft Intune
  • Windows Autopilot
  • Powershell
1 week agoApply ↗
ManTech logo

Senior Cloud System Administrator

ManTech5,001–10,000 employees

Annapolis JunctionOn-site15+ yrs$128k–214k

15+ years systems administrator or cloud engineer experience; bachelor's degree in engineering, computer science, or related field (or 5 additional years experience); IAT II certification (e.g…

  • Windows Server 2019
  • Windows Server 2022
  • Active Directory
  • DNS
1 week agoApply ↗
Trammell McGee-Cooper and Associates logo

Software Engineering Internship (Summer 2027)

Trammell McGee-Cooper and Associates11–50 employees

El SegundoOn-site$62k–104k

Currently pursuing a bachelor's or master's degree in computer science, software engineering, mathematics, physics, or related field; experience with storage systems, cloud infrastructure, and…

  • TypeScript
  • React
  • Go
  • Python
1 week agoApply ↗
Flow Engineering logo

Senior Product Engineer

Flow Engineering11–50 employees

San FranciscoOn-site5+ yrs$190k–250k

5+ years developing production software in cloud environments; hands-on experience with modern LLM providers and tooling; familiarity with prompt design, RAG, evaluation methods, and safety…

  • TypeScript
  • Node.js
  • Python
  • Openai
1 week agoApply ↗
Ripple logo

Senior Security Engineer

Ripple501–1,000 employees

San FranciscoHybrid5+ yrs$172k–215k

5+ years in security operations, detection engineering, or incident response; advanced security knowledge; scripting/automation with Python or SOAR; SIEM and data pipeline experience; EDR, identity…

  • Google Security Operations
  • Tines
  • Python
  • Soar
1 week agoApply ↗
Ripple logo

Staff Software Engineer

Ripple501–1,000 employees

San FranciscoHybrid$212k–265k

Deep backend engineering experience in cloud-native distributed systems; API design (REST/gRPC); cloud platforms (AWS preferred) and container orchestration (Kubernetes, ECS); leadership skills; Java…

  • React
  • Vue
  • REST
  • gRPC
1 week agoApply ↗
Psst.org logo

Software Engineer (Contract)

Psst.org2–10 employees

United StatesRemoteSalary not disclosed

Proficiency in Rust or C++ with systems programming; familiarity with TEEs (Intel SGX, TDX, AWS Nitro Enclaves, Azure/Google Confidential Computing) or ability to learn; secure software development…

  • Rust
  • C++
  • Intel SGX
  • TDX
1 week agoApply ↗
Backblaze logo

Site Reliability Engineer III (DBA)

Backblaze201–500 employees

United StatesRemote6+ yrs$125k–150k

6-8 years SRE/systems/database engineering experience; deep MySQL and distributed database experience; Vitess preferred; Cassandra; Linux; Kubernetes; Docker; Terraform, Ansible, Jenkins; scripting…

  • Vitess
  • MySQL
  • Cassandra
  • Linux
1 week agoApply ↗
Circuit Check logo

Applications Engineering Manager

Circuit Check51–200 employees

Maple GroveOn-site8+ yrs$110k–150k

BS/MS in Electrical Engineering, Computer Science or equivalent; 8+ years in applications/systems engineering for complex products; 3+ years people management; hands-on quoting tool development…

  • Microsoft Excel
  • VBA
  • Python
  • Salesforce
1 week agoApply ↗
The Johns Hopkins University Applied Physics Laboratory logo

Military Systems Cybersecurity Software Engineer

The Johns Hopkins University Applied Physics Laboratory5,001–10,000 employees

LaurelOn-site3+ yrs$100k–195k

Bachelor's in computer science, cybersecurity, or related field; 3+ years software development; proficiency in Python, Java, Golang, Rust, C, or C++; knowledge of cybersecurity principles; ability to…

  • Python
  • Java
  • Go
  • Rust
1 week agoApply ↗
Momentum Engineering logo

ME00692-Software Engineer 1

Momentum Engineering11–50 employees

Annapolis JunctionOn-site$110k–155k

Active TS/SCI clearance with NSA Full Scope Polygraph; experience developing, testing, and integrating software; Python, JavaScript, HTML, CSS, React/Angular/Vue; AWS; Git; Agile; strong…

  • React
  • Angular
  • Vue.js
  • Python
1 week agoApply ↗
Bitgo S.r.l. logo

Senior Security Application Engineer

Bitgo S.r.l.201–500 employees

New York CityOn-site8+ yrs$200k–235k

8+ years engineering security programs; FinTech/Web3 experience; Python or Java; container security, Kubernetes, AWS; SOC 2 Type II and GDPR; AI/ML security; Bachelor's in Computer Science or…

  • Sast
  • Dast
  • Terraform
  • Kubernetes
1 week agoApply ↗
CLERAD logo

Founding Engineer

CLERAD11–50 employees

San FranciscoOn-site2+ yrs$150k–250k

2+ years shipping production software end to end; hands-on LLM/AI agent experience; full-stack/backend skills in TypeScript, Python, Go, Rust; US work authorization without visa sponsorship; on-site…

  • TypeScript
  • Python
  • Go
  • Rust
1 week agoApply ↗
Atlas Copco logo

Embedded Firmware Engineer

Atlas Copco10,000+ employees

HaverhillOn-site5+ yrs$90k–110k

5+ years relevant experience preferred; degree in Computer, Software, or Electrical Engineering; proficiency in C, C++, Linux; embedded controls and RTOS experience; Python/VBA desirable; on-site in…

  • C
  • C++
  • Linux
  • Freertos
1 week agoApply ↗

Python Developer jobs in other cities

  • Bangalore
  • Hyderabad
  • Pune
  • Delhi
  • Mumbai
  • Chennai
  • Remote, India

Python developer jobs in the USA: FAQs

How many Python developer jobs in the USA are open right now?

There are 2,487 open Python developer jobs in the USA on Weekday as of 7 October 2026, with 733 added in the last 7 days. 1 of them were posted on Weekday by the employer and take one step to apply; they are listed first. The list updates daily.

Which companies are hiring for Python developer roles in the USA?

Renesas Electronics, Microsoft, Apple, Cognizant and Oracle have the most open Python developer roles in the USA on Weekday right now. Pick a company under "Top companies hiring" to see only its jobs.

Which skills do Python developer jobs in the USA ask for most?

Among the newest listings, Python, C++, C, Go, Linux and TypeScript come up most often.

Is Weekday free for job seekers?

Yes. Browsing and applying to jobs on Weekday is free for candidates. Companies pay Weekday to hire.

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